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IEEE Buenaventura
March 2019 Newsletter

In This Issue

Local IEEE Events

•  Mar 27: 3D Printing of Organs: Are We There Yet? — CLU, Gilbert Room 253
•  Mar 28: Spring Section Mixer — Reverse Engineer the Brain — Expert Panel Event — Hub101

Other IEEE Announcements

•  Starting March 1, Join IEEE and Save 50%

Other Local Happenings

•  IEEE Employer Members — Be a C.I.T.Y. Host

Job Opportunities and Sponsors

•  Advanced Personnel Profiles — Staffing & Recruiting Since 1995
•  Syntesis Global — Management Consulting
•  Ameriprise Financial — D. F. Rick Speidel, Financial Advisor

Local IEEE Events

March 27, 2019
3D Printing of Organs: Are We There Yet?

Dinner (optional): Available at 6:00 PM for $12, payable at the door.
Presentation (free): 7:00 PM
Speaker: Bill Tawil
Free admission to presentation.

Abstract

In his lab in Department of Bioengineering at UCLA, Dr. Tawil’s research team has focused on understanding the mechanical characteristics of 3D fibrin constructs by using various approaches including diffusion, cross linking, etc.  Furthermore, they have examined cell behavior in 3D fibrin constructs including cell proliferation, differentiation, and migration. The team has examined various cell types including Mesenchymal stem cells, fibroblasts, keratinocytes and osteoblasts. Areas of research include:

1.  3D Constructs to Study Bone Healing:
The construct consists of fibrin, collagen, hydroxyapatite, and β-tricalcium phosphate (F-C-HA-TCP). The research team is now examining the Mesenchymal stem cells proliferation and their differentiation into osteoblasts in this construct.  They are also in the process of establishing a process to examine the controlled release of recombinant human bone morphogenetic proteins (rhBMP) from fibrin beads within the F-C-HA-TCP 3D constructs. The team is identifying the mechanism of action that guides mesenchymal stem cell proliferation and osteogenic differentiation within the 3D biomatrix by examining the expression of integrins and bone morphogenetic protein receptors. Finally, they will implant the 3D biomatrix into a rabbit femoral defect model and examine structural changes, rate of degradation, restoration, mineralization, ossification, and osseointegration.

2.  In Vitro 3D Wound Healing Model:
The research team has established in Vitro 3D wound healing model to study the intricate relationship between the various growth factors and cells that are known to play role in the wound healing process.  The 3D construct consists of 3 components: human dermal – derived fibroblasts incorporated in type I collagen representing the dermis, human dermal keratinocytes seeded on the top of fibroblasts/collagen 3D construct representing the epidermis, and finally a fibrin cylinder (or multiple cylinders) seeded in the middle of the construct representing the wound.  This fibrin cylinder contains one or more growth factors that might influence keratinocytes migration into or under the fibrin cylinder.

3.  Co – Delivering Fibroblasts and Keratinocytes in 3D Fibrin Constructs for the Treatment of Skin Wounds:
The research team is testing the hypothesis that fibrin component concentration, as well as the spatial distribution and proportion of fibroblasts and keratinocytes, all affect cell behavior and signaling relevant to wound healing. These factors are ubiquitous in fibrin-based cell therapies for wound healing, yet have not been thoroughly studied.  This study furthers our understanding of cell-fibrin interactions, and enhances the therapeutic efficacy of fibrin-based cell carriers. To test our hypothesis, fibroblasts are homogeneously seeded in a novel in vitro 3D fibrin construct. Keratinocytes are encapsulated in fibrin beads and suspended in the main 3D fibrin construct to spatially control cell distribution.

About the Speaker

Dr. Bill Tawil obtained his Bachelor degree in Biochemistry from the University of California at Berkeley.  He then completed his Master and Doctorate degrees in Neuroscience at McGill University in Montreal studying the expression and function of adhesion cell surface receptors (integrins) in the Central Nervous System and during tumor metastasis.  Subsequently, he spent four years of postdoctoral training at the Center for Cancer Research at MIT under the supervision of Dr. Richard Hynes investigating cell adhesion during the cell cycle.  As a Scientist and a Senior Scientist at U.S. Surgical Corporation and at Baxter BioSurgery, he worked in the field of Tissue Regeneration examining products (synthetic and biologics) that successfully deliver bioactive substances and cells to enhance healing in soft and hard tissue defects.  He, then, acted as a director of global expansion at Baxter BioSurgery responsible for scientific initiatives related to tissue engineering establishing collaborations between Baxter and other companies and academic institutions.  He, then, hold a Director of R&D position at CR Bard.

Dr. Tawil is presently a director in Program Management at Abbott Medical. Bill is also an adjunct professor in the Bioengineering Department at UCLA where he is continuing his research in Tissue Engineering, specifically on 3D constructs. He is on council for the Tissue Engineering and Regenerative Medicine (TERMIS) – North America society and on the Executive Editorial Board for the Tissue Engineering Journal. Bill was the co – Chair for TERMIS 2008 and 2016 meeting. He has been the treasurer for TERMIS since 2009. Bill served on the BOD for the Wound Healing Society (WHS) from 2000 to 2005 and he was the treasurer from 2002 to 2005.  He was on the Program Committee for the WHS from 1998 – 2000 and again from 2005 – 2008 including the co – chair for the 2007 meeting. Bill believes strongly that the interaction between academia and industry is an expedient and successful way to get products to the patients.

Location

CLU – Gilbert Sports and Fitness Center, 2nd Floor, Room 253
California Lutheran University
130 Overton Court
Thousand Oaks, CA 91360
(map)

Parking: Free parking is available in the lot east of the Gilbert building. Additional free parking is available in the lot on the southwest corner of Olsen and Mountclef. Do not park in the faculty/staff/reserved lots.

Presented by: IEEE Buenaventura Engineering in Medicine and Biology Society Chapter

Visit the EMBS chapter web site for details on other upcoming events


March 28, 2019
Spring Section Mixer — Reverse Engineer the Brain
Expert Panel Event

Dinner Buffet: 6:30 PM
Panel: 7:00 PM to 8:15 PM
Panelists: To be announced
Free admission but registration required: www.ieee-bv.org/meet/2019-03-mixer

Location

Hub101
Cal Lutheran Center for Entrepreneurship
31416 Agoura Road
Westlake Village, CA 91361
(map)

Presented by: IEEE Buenaventura Section

Other IEEE Announcements

Starting March 1, Join IEEE and Save 50%

When you join IEEE, you join a community of over 420,000 technology and engineering professionals united by a common desire to continuously learn, interact, collaborate, and innovate. IEEE membership provides you with the resources and opportunities you need to keep on top of changes in technology; get involved in standards development; network with other professionals in your local area or within a specific technical interest; mentor the next generation of engineers and technologists, and so much more.

Starting March 1, join and get membership benefits through the end of 2019, plus save 50% on membership dues. There is no better time to discover all that IEEE membership has to offer.

Visit the IEEE Membership Services page to join

IEEE Benefits

Keeping Technically Current: Continue to advance your career and keep abreast of new and changing technologies. IEEE has the means for you to remain technically current through award winning publications, and technical societies.

Career Resources and Recognition: Leadership is a skill that must be crafted over time. Keep your career moving in the right direction with IEEE career benefits and resources.

Professional Networking: With other IEEE members who share similar interests, you can build a network revolving around your profession, industry or projects.

Continuing Education: Keep growing with IEEE continuing education benefits and other educational opportunities available to IEEE members. These resources allow you to acquire new skills and advance your professional development.

Discounts: IEEE members enjoy reduced rates on many proprietary products and services including IEEE books and eBooks, journals and articles, conferences and proceedings, standards, society memberships, and continuing education courses. In addition, members have access to a variety of affinity programs that offer savings.

Humanitarian Programs: Volunteering is a rewarding way to develop interpersonal skills, create new professional relationships, and apply your expertise to help others.

IEEE DataPort: IEEE DataPort is an easy-to-use, globally accessible data repository developed and offered by IEEE that provides significant benefits to researchers, data analysts, and the global technical community. The repository is fully functional and currently offers free uploads of datasets up to 2 TB for those that need to retain and manage their valuable research data.

See all the benefits IEEE membership has to offer

Other Local Happenings

IEEE Employer Members — Be a C.I.T.Y. Host
Pay it forward - Contribute to your community

What is C.I.T.Y.?
•  C.I.T.Y. = Community Internships Training Youth, a collaboration of City of Thousand Oaks, Ventura County Office of Education, CLU, Greater Conejo Chamber of Commerce, Conejo Valley USD, Conejo Youth Employment Services
•  C.I.T.Y. provides internship opportunities during the summer for incoming high school seniors in the Greater Conejo Valley

What’s in it for you?
•  Generate positive PR for your company
•  Paying it Forward enhances your employee’s engagement and develops their leadership skills

Here’s what we ask of you:
•  Provide a minimum of 10 hours per week on the job training
•  Internships can be paid or unpaid
•  Provide a workplace mentor who can meet with the intern weekly

Worried about liability?
•  Ventura County Office of Education provides umbrella liability coverage for unpaid internships at no cost to you

What are the next steps?
•  Visit www.toaks.org/city

Questions?
•  Francine Sprigel, City of Thousand Oaks; youthcommission@toaks.org — 805-381-7362
•  Hilary Howard, VCOE; HHoward@vcoe.org — 805-437-8046

Sponsors

Advanced Personnel Profiles
Staffing & Recruiting Since 1995

Job Opportunities

Sr. Software Development Manager
San Jose, CA

Minimum of 10 years of experience in Windows application development using object-oriented techniques using MFC and .Net using multi-threaded programming.  Experience as a software architect or working on a software architecture team, providing technical leadership/guidance/mentorship.  At least 8 years of C/C++ programming experience.  Experience in motion control, digital signal processing, hardware interfaces, and interactive GUIs.

Contact Pat Jacobs — 805-579-0630 pat.jacobs@advancedpersonnelprofiles.com

Electrical Engineer - ASIC Layout
Second Sight (www.secondsight.com), Sylmar, CA

Working as the main layout engineer, collaborate with ASIC circuit design engineers on architectural design and floor planning, and carry out most of the chip circuit layout work.   Also responsible for PCB layout for chip testing circuits, and plays a supporting role in chip testing.

•  EE BSc degree with at least four years of experience or MSc degree with at least two years of experience in comprehensive CMOS chip layout work that includes chip level layout, DRC and LVS
•  Good understanding of CMOS fabrication processes
•  Good understanding of principles of CMOS devices and circuits

Contact Pat Jacobs — 805-579-0630 pat.jacobs@advancedpersonnelprofiles.com

Electrical Engineer
Second Sight (www.secondsight.com), Sylmar, CA

Researches and develops systems, designs circuits, and tests electrical components, equipment, and systems.  Must have experience with:
•  design and simulation software (e.g. SPICE, VHDL or Verilog, Altium)
•  design control
•  verification and validation testing and documentation
•  medical device industry or pharmaceutical industry is critical
•  5 years related experience and/or training

Contact Pat Jacobs — 805-579-0630 pat.jacobs@advancedpersonnelprofiles.com

Principal Mechanical Engineer
Second Sight (www.secondsight.com), Sylmar, CA

There are two positions for mechanical engineers – at the Principal and Senior levels.  Must have medical device experience, able to develop engineering drawings using 2D and 3D CAD software (e.g. AutoCad and SolidWorks) and willing to work hands-on.  May have some supervisory responsibilities.

Contact Pat Jacobs — 805-579-0630 pat.jacobs@advancedpersonnelprofiles.com

Sr. Software Engineer (FullStack)
Second Sight (www.secondsight.com), Sylmar, CA

There are two openings for Sr. Full Stack Software Developer with strong knowledge of JavaScript, Angular 4+, HTML5, REST/WebSockets.  Prefer experience in an agile development cycle, cloud based systems and work in a regulated industry.

Contact Pat Jacobs — 805-579-0630 pat.jacobs@advancedpersonnelprofiles.com

Sr. Software Test Engineer
Second Sight (www.secondsight.com), Sylmar, CA

Sr. Software Test Engineer experienced developing, documenting and executing manual and automated verification and validation tests.  Proficiency with front and back end applications.  Experience with high level scripting such as Python, BASH, or MatLab.  Linux/Unix experience.  Prefer experience with medical device testing or other regulated industries.

Contact Pat Jacobs — 805-579-0630 pat.jacobs@advancedpersonnelprofiles.com


Syntesis Global
Management Consulting

Syntesis Global introduces the “New Standard” for Creating a Culture of Excellence in Leadership Development, Organizational Dynamics, Career Transitions and Outplacement Services: Syntesis Global™. With over thirty years of business experience, Syntesis Global™ offers state-of-the-art Performance Consulting through Executive Coaching, Change Management, Team Building, Organizational and Career Management services. Contact Rick Hernandez, President and CEO at contactus@syntesisglobal.com


Ameriprise Financial

D. F. Rick Speidel, Financial Advisor
Managing Director
Ameriprise Financial Services, Inc.
3027 Townsgate Rd Suite 200
Westlake Village, CA 91361-5863
O: 805.367.9015|F: 805.277.5156
Toll Free: 866.301.0449
CA Insurance License #0A01366
www.ameripriseadvisors.com/denny.f.speidel

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